产品货号：
Z39500
中文名称：
PTBP1抗体
英文名称：
Anti-PTBP1 Antibody (Clone#3H12)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-PTBP1 Antibody (Clone#3H12) |
| 指标别名 | HNRNP I;HNRNPI;HNRPI;pPTB;PTB;PTB 1;PTB T;PTB2;PTB3;PTB4;PTBP1 |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,ICC/IF,FCM |
| 基因名称 | PTBP1 |
| 克隆号 | 3H12 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG2b |
| 免疫原 | E.coli-derived human PTBP1 recombinant protein (Position:M1-A504). |
| 实际分子量 | 57KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | protein G purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Polypyrimidine tract-binding protein 1 is a protein that in humans is encoded by the PTBP1 gene.It is mapped to 19p13.3.This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs).The hnRNPs are RNA-binding proteins and they complex with heterogeneous nuclear RNA (hnRNA).These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport.While all of the hnRNPs are present in the nucleus,some seem to shuttle between the nucleus and the cytoplasm.The hnRNP proteins have distinct nucleic acid binding properties.The protein encoded by this gene has four repeats of quasi-RNA recognition motif (RRM) domains that bind RNAs.This protein binds to the intronic polypyrimidine tracts that requires pre-mRNA splicing and acts via the protein degradation ubiquitin-proteasome pathway.It may also promote the binding of U2 snRNP to pre-mRNAs.This protein is localized in the nucleoplasm and it is also detected in the perinucleolar structure.Alternatively spliced transcript variants encoding different isoforms have been described. |
| Uniprot ID | P26599 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (ZN1928) for Western blot,and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (ZN1866) for IHC(P) and ICC. |
| 基因名全称 | polypyrimidine tract binding protein 1 |
| 蛋白名全称 | Polypyrimidine tract-binding protein 1 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
相关搜索：PTBP1抗体，PTBP1单抗，Anti-PTBP1 Antibody (Clone#3H12)